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The Changing Face of Childhood Nephrotic Syndrome

What Is Nephrotic Syndrome?

Nephrotic syndrome is a severe kidney disorder that causes the body to excrete excess protein in the urine. Small blood vessels in the kidneys that filter waste and excess water from the blood are broken; thereby begin swelling in the feet and ankles.

Nephrotic syndrome is a condition marked by:

  • Proteinuria—large amounts of protein in the urine
  • Hyperlipidemia—advanced than healthy fat and cholesterol stages in the blood
  • Edema, or swelling, usually in the legs, feet, or ankles and less often in the hands or face
  • Hypoalbuminia—low levels of albumin in the blood

Nephrotic Syndrome Definition

Nephrotic syndrome is most often caused by one of two idiopathic diseases: minimal change nephrotic syndrome (MCNS) and focal segmental glomerulosclerosis (HSF). A third diverse type, membranous nephropathy, is rare in children.

Other causes of nephrotic syndrome isolated can subdivide into two significant categories: disorders, rare genetic and secondary diseases associated with drugs or infections.

Here's What Should Know to Identify about Nephrotic Syndrome

Nephrotic syndrome child is also called nephrosis. In the vast majority of a child with nephrotic syndrome means that doctors require advanced treatment to know what causes it. Nephrotic syndrome always affects both kidneys.

It usually appears between the early years and primary school, although it may appear later. It is not believed that there are two forms of nephrotic syndrome, minimal change disease (MCD) and focal sclerosis.

MCD is much more common in children and is likely to respond to therapy. Most of the nephrotic syndrome in children is growing faster than by young adulthood.

Treating Children with Nephrotic Syndrome

The kidneys usually function as a filter to keep the proteins in the blood, while waste products are filtered out. When the kidneys do not work correctly, the protein is filtered out of the blood and urine. When a large amount of protein in the urine escapes and affects the results of your blood tests. These measures call for nephrotic syndrome children.

What Causes Nephrotic Syndrome?

Nephrotic syndrome causes results in damage to the kidneys' glomeruli. These are the small blood vessels that filter waste and excess water from the blood and send them to the bladder as urine.
Nephrotic syndrome can occur with other health problems such as kidney disease caused by diabetes and immune disorders. It can also develop after damage caused by viral infections.

What Are The Symptoms of Nephrotic Syndrome?

Nephrotic syndrome is a set of symptoms. These are the most common:
  • High blood pressure
  • Swollen feet and hands, and around the eyes
  • Weight gain with fluid retention and swelling
  • Indication of infection such as fever, or white blood cell count
  • Foamy urine that appears from the loss of body protein in the urine voided

Long-Term Outlook for Nephrotic Syndrome

Relapses do occur throughout childhood. On the other hand, once the child reaches puberty, the disease usually remains in complete remission or partial absence of symptoms. It is uncommon for symptoms to return during adulthood; however, it is possible.

What Is The Treatment For Nephrotic Syndrome?

Dr. B. Vijay Kiran will figure out the best nephrotic syndrome treatment based on:
  • How old you are
  • Your overall health and medical history
  • How well you can handle detailed medications, measures, or therapies
  • How long it is expected that the last condition

Dr. B. Vijay Kiran will try to find the underlying cause. He will also attempt to control blood pressure and cholesterol, and reduce protein in the urine.

Medicines can include: 

  • ACE inhibitors and angiotensin receptor blockers:  These lower blood pressure and may be used in people with diabetes to protect the kidneys.
  • Corticosteroids: These may be recommended to condense swelling and inflammation within the glomerulus. These help tostop your immune system from attacking healthy tissue.
  • Immune system modifying medicines: This type of medication is used to keep your immune system to attack the glomeruli.
  • Cholesterol-lowering medicines: These can be recommended if your triglycerides and cholesterol are high.
  • Antibiotics or antiviral medicines: These are used to treat the fundamental infectious cause.
  • Diet: A particular diet may help postponement the necessity for dialysis and to get rid of excess fluid and toxins that accumulate.  Avoid fat and cholesterol. Be sure to eat lean protein.
Dialysis is used in extreme cases to remove toxins and fluids when kidneys have severely deteriorated filtration.

Know Your Expert

Experiencing swollen legs and foamy urine? It might be nephrotic syndrome. Dr. B. Vijay Kiran is a well-known nephrologist based in Hyderabad
Dr. B. Vijay Kiran dedication to health care, particularly in the field of Nephrology, has earned him respect within all associations, hospitals, and organizations he is affiliated with

Take the Next Step

Schedule an appointment by calling at +919247701326 to get the best consultation with Dr.B. Viay Kiran. Request information regarding clinical trials at OPD Room #16Old Block, NIMS, Punjagutta, Telangana, India, 500082


  1. I got replaced my kidney under the treatment of Dr.B.Vijay Kiran. He is really the best nephrologist in Hyderabad. Now I am living with no issues, so I would like to give a big thank to dr.b.vijay kiran. Patients with any kind of kidney issue can contact Dr.B.Vijay Kiran in Hyderabad, India. His website is live now. Go through here to get more details of the doctor. Patients can also contact him to book appointment or any kind of suggestions. Contact Number: +91 924 770 1326


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